SGT-78

SGT-78

140.006,500.00

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140.006,500.00

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  • Description
  • CHEMICAL DATA
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Description

Pharmacokinetics:

SGT-78 is a synthetic cannabinoid that also goes by the names CYMYL-4CN-BINACA and CUMYL-CYBINACA. It’s an indazole-3-carboxamide-based compound with the formal name 1-(4-cyanobutyl)-N-(1-methyl-1-phenylethyl)-1H-indazole-3-carboxamide (C22H24N4O) [1]. SGT-78 produces highly evident physiological and psychoactive effects. Research shows it has a high affinity for binding with cannabinoid receptors CB1 and CB2, but it favors CB1 receptors. In comparing SGT-78 with its closely related SGT-25 (5F-CUMYL-PINACA), researchers found SGT-78 to be more potent, forming a tighter bind with cannabinoid receptors [2].

Scientific Studies:

In a 2019 study published in “Frontiers in Pharmacology,” researchers looked at the effects of SGT-78 on mice. They found that the effects of it binding so tightly to CB1 receptors can have convulsant effects and produce a hypothermic reaction. Notably, the researchers concluded that these effects occurred at a dose lower than has been reported for any other synthetic cannabinoid, suggesting it operates within the endocannabinoid system at a high level of potency [2].

Another study, published in 2018 in “Drug Test Analysis,” found that when the body metabolizes SGT-78, it produces the deadly toxin cyanide as a byproduct [3].

Sources:

1. https://www.caymanchem.com/product/20194

2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549035/

3. https://www.ncbi.nlm.nih.gov/pubmed/29577658

IUPAC NameCYMYL-4CN-BINACA, CUMYL-CYBINACA
CAS Number1631074-54-8
Formula

C22H24N4O

Molar Mass

360.461 g·mol−1

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